A pyroptosis‐related signature predicts prognosis and indicates immune microenvironment infiltration in glioma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5247
Abstract: Glioma, the most common malignant brain tumor, leads to high recurrence rates and disabilities in patients. Pyroptosis is an inflammasomes‐induced programmed cell death in response to infection or chemotherapy. However, the role of pyroptosis in… read more here.
Keywords: pyroptosis; signature predicts; related signature; pyroptosis related ... See more keywords
A pyroptosis‐related lncRNA signature in bladder cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5344
Abstract: Pyroptosis, a type of programmed cell death, is implicated in the tumorigenesis, development and migration of cancer, which can be regulated by long non‐coding RNAs (lncRNAs). Our research aimed to investigate the prognostic role of… read more here.
Keywords: related lncrna; signature bladder; pyroptosis; pyroptosis related ... See more keywords
Potentially functional variants of CHMP4A and PANX1 in the pyroptosis‐related pathway predict survival of patients with non‐oropharyngeal head and neck squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23767
Abstract: Pyroptosis has been implicated in the advancement of various cancers. Triggering pyroptosis within tumors amplifies the immune response, thereby fostering an antitumor immune environment. Nonetheless, few published studies have evaluated associations between functional variants in… read more here.
Keywords: patients non; oropharyngeal head; pyroptosis; pyroptosis related ... See more keywords
Pyroptosis-related long-noncoding RNA signature predicting survival and immunotherapy efficacy in patients with lung squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-024-01409-w
Abstract: Pyroptosis-related long-noncoding RNAs (PRlncRNAs) play an important role in cancer progression. However, their role in lung squamous cell carcinoma (LUSC) is unclear. A risk model was constructed using the least absolute shrinkage and selection operator… read more here.
Keywords: pyroptosis related; analysis; risk; long noncoding ... See more keywords
A pyroptosis-related lncRNA signature predicts prognosis and immune microenvironment in head and neck squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108268
Abstract: BACKGROUND Pyroptosis, a type of regulated cell death controlled by the gasdermin family of proteins to form plasma membrane pores is known. Nonetheless, the function of pyroptosis-related long non-coding RNAs (lncRNAs) in this process still… read more here.
Keywords: risk; pyroptosis; lncrna signature; cell ... See more keywords
Identification of pyroptosis-related gene signature in nonalcoholic steatohepatitis
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-53599-8
Abstract: Non-alcoholic fatty liver disease (NAFLD) has emerged as one of the major causes of liver-related morbidity and mortality globally. It ranges from simple steatosis to non-alcoholic steatohepatitis (NASH) characterized by ballooning and hepatic inflammation. In… read more here.
Keywords: pyroptosis; pyroptosis related; related genes; nash ... See more keywords
Machine learning analysis of gene expression profiles of pyroptosis-related differentially expressed genes in ischemic stroke revealed potential targets for drug repurposing
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-024-83555-5
Abstract: The relationship between ischemic stroke (IS) and pyroptosis centers on the inflammatory response elicited by cerebral tissue damage during an ischemic stroke event. However, an in-depth mechanistic understanding of their connection remains limited. This study… read more here.
Keywords: ischemic stroke; stroke; gene expression; pyroptosis related ... See more keywords
Design and optimization of caspase-1-responsive fluorescent probes for pyroptosis imaging and anti-pyroptosis drug screening.
Sign Up to like & getrecommendations! Published in 2025 at "Chemical science"
DOI: 10.1039/d5sc07690k
Abstract: Pyroptosis is a recently-identified form of inflammatory caspase-dependent programmed cell death that is closely associated with many diseases. Real-time imaging of pyroptosis is crucial for monitoring the inflammatory pathological process. Caspase-1, a representative of inflammatory… read more here.
Keywords: pyroptosis; pyroptosis related; design optimization; caspase ... See more keywords
Development and validation of pyroptosis-related lncRNAs prediction model for bladder cancer
Sign Up to like & getrecommendations! Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20212253
Abstract: Abstract Bladder cancer (BLCA) is one of the highly heterogeneous disorders accompanied by a poor prognosis. The present study aimed to construct a model based on pyroptosis-related long-stranded non-coding RNA (lncRNA) to evaluate the potential… read more here.
Keywords: pyroptosis related; risk; bladder cancer; cancer ... See more keywords
Two Pyroptosis-Related Subtypes with Distinct Immune Microenvironment Characteristics and a Novel Signature for Predicting Immunotherapy Response and Prognosis in Uveal Melanoma.
Sign Up to like & getrecommendations! Published in 2022 at "Current eye research"
DOI: 10.1080/02713683.2022.2048396
Abstract: PURPOSE Uveal melanoma (UM) is the most common primary intraocular malignant tumor in adults with poor prognosis. Pyroptosis is a well-known form of programmed cell death. However, pyroptosis has not been sufficiently discussed in UM.… read more here.
Keywords: response; uveal melanoma; prognosis; pyroptosis ... See more keywords
Significance of pyroptosis-related genes in the diagnosis and classification of diabetic kidney disease
Sign Up to like & getrecommendations! Published in 2024 at "Renal Failure"
DOI: 10.1080/0886022x.2024.2409331
Abstract: Abstract Objective This study aimed to identify the potential biomarkers associated with pyroptosis in diabetic kidney disease (DKD). Methods Three datasets from the Gene Expression Omnibus (GEO) were downloaded and merged into an integrated dataset.… read more here.
Keywords: pyroptosis; pyroptosis related; related genes; kidney disease ... See more keywords