Preparation of novel pyrrol-2-one derivatives via an effective synthesis of new oxazole scaffold
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DOI: 10.1016/j.tet.2017.01.046
Abstract: Abstract A convenient procedure for the preparation of oxazole and pyrrole derivatives is described. 2-Amino-1,3-oxazol-2-ones 3a,b were first synthesized from the cyclocondensation reactions of cyanamide (2) with 4-ethoxycarbonyl-5-aryl-2,3-furandione 1a,b, and then new pyrrol-2-ones 5 were… read more here.
Keywords: preparation novel; one derivatives; pyrrol; pyrrol one ... See more keywords
Design and synthesis of novel 3-(thiophen-2-yl)-1,5-dihydro-2H-pyrrol-2-one derivatives bearing a hydrazone moiety as potential fungicides
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DOI: 10.1186/s13065-018-0452-z
Abstract: BackgroundTetramic acid, thiophene and hydrazone derivatives were found to exhibit favorable antifungal activity. Aiming to discover novel template molecules with potent antifungal activity, a series of novel 3-(thiophen-2-yl)-1,5-dihydro-2H-pyrrol-2-one derivatives containing a hydrazone group were designed,… read more here.
Keywords: pyrrol one; dihydro pyrrol; thiophen dihydro; antifungal activity ... See more keywords