Pyrrole ring opening – pyridine ring closure: Recyclization of 2-(2-oxo-1,2-dihydro-3H-pyrrol-3-ylidene)malononitriles into highly functionalized nicotinonitriles
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DOI: 10.1016/j.tetlet.2019.151368
Abstract: Abstract A series of novel N,N-dialkyl-2-amino-3-cyanoisonicotinamides were synthesized in good to high yields (61–84%) via the reaction of 2-(5-aryl-2-oxo-1H-pyrrol-3(2H)-ylidene)malononitriles and amines according to the ANRORC process. The developed approach represents a novel method for the… read more here.
Keywords: ylidene malononitriles; functionalized nicotinonitriles; pyrrole ring; pyrrol ylidene ... See more keywords
Synthesis of 2-(3-cyano-5-hydroxy-5-methyl-4-vinylene-1H-pyrrol-2(5H)-ylidene)malononitriles – novel functionalized analogs of tricyanofuran-containing (TCF) push–pull chromophores
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DOI: 10.1080/00397911.2018.1500426
Abstract: Abstract 2-(3-Cyano-5-hydroxy-4,5-dimethyl-1H-pyrrol-2(5H)-ylidene)malononitrile was synthesized by the interaction between malononitrile dimer and diacetyl. It reacts with aldehydes in ethanol in the presence of ammonium acetate at room temperature and results 2-(3-cyano-5-hydroxy-5-methyl-4-vinylene-1H-pyrrol-2(5H)-ylidene)malononitriles in 66–86% yield. The developed… read more here.
Keywords: methyl vinylene; hydroxy methyl; cyano hydroxy; pyrrol ylidene ... See more keywords