Articles with "pyrrole carboxamide" as a keyword



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2-Phenyl-1H-pyrrole-3-carboxamide as a New Scaffold for Developing 5-HT6 Receptor Inverse Agonists with Cognition-Enhancing Activity

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Published in 2021 at "ACS Chemical Neuroscience"

DOI: 10.1021/acschemneuro.1c00061

Abstract: Serotonin type 6 receptor (5-HT6R) has gained particular interest as a promising target for treating cognitive deficits, given the positive effects of its antagonists in a wide range of memory impairment paradigms. Herein, we report… read more here.

Keywords: cognition enhancing; inverse agonists; phenyl pyrrole; ht6r ... See more keywords