Articles with "pyrrole derivative" as a keyword



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A rainbow multielectrochromic copolymer based on 2,5-di(thienyl)pyrrole derivative bearing a dansyl substituent and 3,4-ethylenedioxythiophene

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Published in 2020 at "Synthetic Metals"

DOI: 10.1016/j.synthmet.2020.116545

Abstract: Abstract A 2,5-di(thienyl)pyrrole derivative bearing a dansyl substituent (SNSD) was prepared by a simple synthetic route and its copolymerization with 3,4-ethylenedioxythiophene (EDOT) was successfully performed electrochemically in acetonitrile (CH3CN) containing tetrabutylammonium tetrafluoroborate ((C4H9)4NBF4). The electrochromic… read more here.

Keywords: thienyl pyrrole; derivative bearing; dansyl substituent; pyrrole derivative ... See more keywords
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A novel calix[4]pyrrole derivative as a potential anticancer agent that forms genotoxic adducts with DNA

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-29314-9

Abstract: Abstractmeso-(p-acetamidophenyl)-calix[4]pyrrole 3 was found to exhibit remarkable cytotoxicity towards A549 cancer cells. A comparative study including the isomer of 3meso-(m-acetamidophenyl)-calix[4]pyrrole 5, as well as molecules containing ‘fragments’ of these structures, demonstrated that both the calix[4]pyrrole… read more here.

Keywords: pyrrole derivative; calix pyrrole; novel calix; calix ... See more keywords
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Comparative Analysis of the Antineoplastic Activity of C60 Fullerene with 5-Fluorouracil and Pyrrole Derivative In Vivo

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Published in 2017 at "Nanoscale Research Letters"

DOI: 10.1186/s11671-016-1775-0

Abstract: The antitumor activity of pristine C60 fullerene aqueous solution (C60FAS) compared to 5-fluorouracil (5-FU) and pyrrole derivative 1-(4-Cl-benzyl)-3-Cl-4-(CF3-fenylamino)-1H-pyrrol-2.5-dione (MI-1) cytostatic drugs was investigated and analyzed in detail using the model of colorectal cancer induced by… read more here.

Keywords: fluorouracil pyrrole; c60 fullerene; activity; pyrrole derivative ... See more keywords
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Tetrasubstituted Pyrrole Derivative Mimetics of Protein–Protein Interaction Hot-Spot Residues: A Promising Class of Anticancer Agents Targeting Melanoma Cells

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28104161

Abstract: A new series of tetrasubstituted pyrrole derivatives (TSPs) was synthesized based on a previously developed hypothesis on their ability to mimic hydrophobic protein motifs. The resulting new TSPs were endowed with a significant toxicity against… read more here.

Keywords: melanoma; tetrasubstituted pyrrole; hot spot; spot residues ... See more keywords