Annulation of 1H-pyrrole-2,3-diones by thioacetamide: an approach to 5-azaisatins
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DOI: 10.3762/bjoc.15.32
Abstract: A novel approach to 1H-pyrrolo[3,2-c]pyridine-2,3-diones (5-azaisatins) has been developed via an unprecedented annulation of pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones by thioacetamide. A new way of C–H functionalization of thioacetamide has been discovered. The reaction proceeds under green catalyst-free conditions. read more here.
Keywords: approach azaisatins; annulation pyrrole; diones thioacetamide; approach ... See more keywords
A facile approach to spiro[dihydrofuran-2,3'-oxindoles] via formal [4 + 1] annulation reaction of fused 1H-pyrrole-2,3-diones with diazooxindoles
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DOI: 10.3762/bjoc.18.162
Abstract: There has been developed an easy synthetic approach to spiro[dihydrofuran-2,3'-oxindoles] via a highly diastereoselective formal [4 + 1] cycloaddition reaction of [e]-fused 1H-pyrrole-2,3-diones with diazooxindoles. The described novel heterocyclic systems are heteroanalogues of antimicrobial and… read more here.
Keywords: pyrrole diones; oxindoles via; reaction; spiro dihydrofuran ... See more keywords