Articles with "pyrrolidines phosphine" as a keyword



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Enantioselective Synthesis of Pyrrolidines by a Phosphine-Catalyzed γ-Umpolung/β-Umpolung Cascade.

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Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c00785

Abstract: Herein, we report an enantioselective catalytic annulation of electron-poor allenes with aminocrotonates. The reaction proceeds by the umpolung γ-amination of the allenoate and β-umpolung intramolecular conjugate addition. The reaction provides ready access to pyrrolidines using… read more here.

Keywords: umpolung umpolung; enantioselective synthesis; synthesis pyrrolidines; pyrrolidines phosphine ... See more keywords