ACID-CATALYZED REARRANGEMENT OF 1-ACYL-2-AZABUTA-1,3-DIENES TO 4-PYRROLIN-2-ONES
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/5861
Abstract: 1-Acyl-2-azabuta-1,3-dienes underwent rearrangement to 4-pyrrolin-2-ones in the presence of acidic catalysts (silica gel or ZnCl 2 ) and water. The reaction proceeded via the formation of 2,3-dihydroxy-3,4-dihydropyrrole and 2-hydroxy-2 Н -pyrrole intermediates, the latter of… read more here.
Keywords: acyl azabuta; pyrrolin ones; acid catalyzed; azabuta dienes ... See more keywords
Catalytic asymmetric de novo construction of 4-pyrrolin-2-ones via intermolecular formal [3+2] cycloaddition of azoalkenes with azlactones.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc01194a
Abstract: The chiral phosphoric acid-catalyzed asymmetric intermolecular formal [3+2] cycloaddition of azoalkenes with azlactones has been established. This convergent protocol leads to a facile and enantioselective de novo construction of a wide range of fully substituted… read more here.
Keywords: azoalkenes azlactones; intermolecular formal; formal cycloaddition; novo construction ... See more keywords
Synthesis of 5-Aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones
Sign Up to like & getrecommendations! Published in 2018 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363218050110
Abstract: Abstract5-Aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones were synthesized by a three-component reaction of methyl aroylpyruvate with a mixture of aromatic aldehyde and 2-aminoacetonitrile sulfate in glacial acetic acid in the presence of anhydrous sodium acetate. read more here.
Keywords: pyrrolin ones; cyanomethyl pyrrolin; hydroxy cyanomethyl; aroyl hydroxy ... See more keywords