Design and synthesis of novel pyrrolo[2,3-a]carbazoles: 7-Chloro-2-oxo-3a-(2'-oxo-2',3'-dihydro-1'H-indol-3'-yl)-2,3,3a,4,5,10-hexahydro-pyrrolo[3,2-a]carbazole-1-carbonitrile as an efficient anticancer agent.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.03.056
Abstract: Highly efficient poly functionalized pyrrolo[3,2-a]carbazoles via ring contraction through rearrangement and intramolecular Michael addition reaction using one pot multicomponent reaction (MCR) is reported for the first time. Free radical scavenging and anticancer activities were determined… read more here.
Keywords: pyrrolo carbazoles; pyrrolo; chloro oxo; anticancer ... See more keywords
Synthesis of pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones via addition/cyclization reactions between 3-chloro-4-indolylmaleimides and alkynes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Chemical Research"
DOI: 10.1177/1747519820909456
Abstract: 3-Chloro-4-indolylmaleimides and two different alkynes are used as the starting materials in a novel and highly effective Pd-catalyzed addition/C–H activation/cyclization sequence for the synthesis of pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones. The desired products are obtained in moderate to excellent… read more here.
Keywords: addition; synthesis pyrrolo; cyclization; carbazole diones ... See more keywords