Articles with "pyrrolo indol" as a keyword



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Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28031269

Abstract: Mutant EGFR/BRAF pathways are thought to be crucial targets for the development of anticancer drugs since they are over-activated in several malignancies. We present here the development of a novel series of 5-chloro-indole-2-carboxylate 3a–e, 4a–c… read more here.

Keywords: indole carboxylate; pyrrolo indol; carboxylate pyrrolo; chloro indole ... See more keywords