Escherichia coli aceE variants coding pyruvate dehydrogenase improve the generation of pyruvate‐derived acetoin
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DOI: 10.1002/elsc.202200054
Abstract: Several chromosomally expressed AceE variants were constructed in Escherichia coli ΔldhA ΔpoxB ΔppsA and compared using glucose as the sole carbon source. These variants were examined in shake flask cultures for growth rate, pyruvate accumulation,… read more here.
Keywords: coli acee; escherichia coli; acee variants; pyruvate derived ... See more keywords
Metabolic Engineering of Microorganisms to Produce Pyruvate and Derived Compounds
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DOI: 10.3390/molecules28031418
Abstract: Pyruvate is a hub of various endogenous metabolic pathways, including glycolysis, TCA cycle, amino acid, and fatty acid biosynthesis. It has also been used as a precursor for pyruvate-derived compounds such as acetoin, 2,3-butanediol (2,3-BD),… read more here.
Keywords: metabolic engineering; pyruvate derivatives; derived compounds; pyruvate derived ... See more keywords