Spectrally selective bSSFP using off-resonant RF excitations permits high spatiotemporal resolution 3D metabolic imaging of hyperpolarized [1-13 C]Pyruvate-to-[1-13 C]lactate conversion.
Sign Up to like & getrecommendations! Published in 2023 at "Magnetic resonance in medicine"
DOI: 10.1002/mrm.29676
Abstract: PURPOSE To develop a high spatiotemporal resolution 3D dynamic pulse sequence for preclinical imaging of hyperpolarized [1-13 C]pyruvate-to-[1-13 C]lactate metabolism at 7T. METHODS A standard 3D balanced SSFP (bSSFP) sequence was modified to enable alternating-frequency… read more here.
Keywords: pyruvate lactate; bssfp; spatiotemporal resolution; lactate ... See more keywords
NIMG-57. SERIAL HYPERPOLARIZED 13C PYRUVATE AND 1H METABOLIC IMAGING IN RECURRENT HIGH-GRADE GLIOMA
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.726
Abstract: Hyperpolarized (HP) 13C MRI is a novel metabolic imaging that allows for real time in vivo probing of pathway-specific metabolic processes relevant to gliomas. The first human brain application reports were published recently. In this… read more here.
Keywords: glioma; pyruvate; lactate conversion; hyperpolarized 13c ... See more keywords