The G‐protein‐biased agents PZM21 and TRV130 are partial agonists of μ‐opioid receptor‐mediated signalling to ion channels
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DOI: 10.1111/bph.14702
Abstract: Opioids remain the most efficient medications against severe pain; they act on receptors that couple to heterotrimeric G‐proteins in the Gαi/o family. Opioids exert many of their acute effects through modulating ion channels via Gβγ… read more here.
Keywords: ion channels; pzm21 trv130; agents pzm21; biased agents ... See more keywords