Identification of a radical SAM enzyme involved in the synthesis of archaeosine.
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DOI: 10.1038/s41589-019-0390-7
Abstract: Archaeosine (G+), 7-formamidino-7-deazaguanosine, is an archaea-specific modified nucleoside found at the 15th position of tRNAs. In Euryarchaeota, 7-cyano-7-deazaguanine (preQ0)-containing tRNA (q0N-tRNA), synthesized by archaeal tRNA-guanine transglycosylase (ArcTGT), has been believed to be converted to G+-containing… read more here.
Keywords: q0n trna; radical sam; sam enzyme; sam ... See more keywords