Salmon‐coloured granules in residual acute myeloid leukaemia with t(8;21)(q22;q22.1); RUNX1‐RUNX1T1
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Haematology"
DOI: 10.1111/bjh.17307
Abstract: A 27-year-old female with a history of acute myeloid leukaemia (AML) with t(8;21)(q22;q22.1); RUNX1-RUNX1T1, in remission, presented for routine bone marrow (BM) followup. Her full blood count was normal. The BM aspirate film, however, showed… read more here.
Keywords: runx1 runx1t1; salmon coloured; coloured granules; q22 ... See more keywords
Genetic Heterogeneity of t(8;21)(q22;q22.1) Acute Myeloid Leukemia Revealed By High-Throughput Targeted Sequencing
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.2688.2688
Abstract: Background: Recently, a comprehensive high-throughput sequencing study of pediatric and adult core-binding factor (CBF) AML [t(8;21), n=85; inv(16), n=80] provided novel aspects of the genetic heterogeneity and disease biology of t(8;21) AML (Faber et al.… read more here.
Keywords: research; q22; research funding; honoraria ... See more keywords
Acute myeloid leukemia patients with variant or unusual translocations involving chromosomes 8 and 21 – A comprehensive cytogenetic profiling of three cases with review of literature
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_190_21
Abstract: Background: t(8;21)(q22;q22) is the most frequent recurrent translocation in acute myeloid leukemia (AML) resulting in an in-frame fusion of RUNX1/RUNX1T1 that regulates various genes involved in the signaling pathways. This leukemogenic alteration is usually associated… read more here.
Keywords: q22; myeloid leukemia; three cases; variant unusual ... See more keywords