Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntington’s Disease
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DOI: 10.1371/journal.pone.0234394
Abstract: In the BACHD mouse model of Huntington’s disease (HD), deletion of the N17 domain of the Huntingtin gene (BACHDΔN17, Q97) has been reported to lead to nuclear accumulation of mHTT and exacerbation of motor deficits,… read more here.
Keywords: model huntington; bachd n17; q97; mouse model ... See more keywords