Development of bioactive compounds-loaded chitosan films by using a QbD approach – A novel and potential wound dressing material
Sign Up to like & getrecommendations! Published in 2019 at "Reactive and Functional Polymers"
DOI: 10.1016/j.reactfunctpolym.2019.02.013
Abstract: Abstract In the present study, a Quality by Design (QbD) approach was applied in order to develop and optimize a chitosan film formulation loaded with bioactive compounds, intended for further use as an aid in… read more here.
Keywords: formulation; chitosan films; qbd approach; film ... See more keywords
QbD APPROACH IN THE DEVELOPMENT OF ORAL LYOPHILISATES WITH IBUPROFEN FOR PAEDIATRIC USE
Sign Up to like & getrecommendations! Published in 2018 at "Farmacia"
DOI: 10.31925/farmacia.2018.3.18
Abstract: Quality-by-Design (QbD) concept in drug formulation and development was introduced in order to achieve and ensure an adequate product quality through a good process understanding. By identifying the variability sources that influence the product features,… read more here.
Keywords: paediatric use; product; time; qbd approach ... See more keywords
The Use of the QbD Approach to Optimize the Co-Loading of Simvastatin and Doxorubicin in Liposomes for a Synergistic Anticancer Effect
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DOI: 10.3390/ph15101211
Abstract: The present study aimed to optimize a liposomal formulation co-encapsulating simvastatin (SIM) and doxorubicin (DOX) that has future perspectives in anticancer therapy. The optimization process was performed by implementing the Quality by Design concept and… read more here.
Keywords: effect; formulation; use qbd; optimal formulation ... See more keywords
Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach
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DOI: 10.3390/ph15121463
Abstract: The present study aims to design and optimize the lornoxicam dispersible tablet (LXDT) formulation using the Quality by design (QbD) approach. A randomized Box–Behnken experimental design was used to characterize the effect of the critical… read more here.
Keywords: qbd approach; design; lornoxicam dispersible; using quality ... See more keywords
Optimization of the Micellar-Based In Situ Gelling Systems Posaconazole with Quality by Design (QbD) Approach and Characterization by In Vitro Studies
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DOI: 10.3390/pharmaceutics14030526
Abstract: Background: Fungal ocular infections can cause serious consequences, despite their low incidence. It has been reported that Posaconazole (PSC) is used in the treatment of fungal infections in different ocular tissues by diluting the oral… read more here.
Keywords: optimization micellar; situ gelling; qbd approach; based situ ... See more keywords
Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Metformin Hydrochloride in Tablet Dosage Forms by HPLC
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DOI: 10.3390/pharmaceutics14061187
Abstract: The current studies entail quality by design (QbD)-enabled development of a simple, rapid, precise, accurate, and cost-effective high-performance liquid chromatographic method for estimation of metformin hydrochloride (M-HCl). Design of experiments (DoE) was applied for multivariate… read more here.
Keywords: qbd approach; design; method; estimation ... See more keywords