Specificity of QuantiFERON-TB Plus, a New-Generation Interferon Gamma Release Assay
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.00629-18
Abstract: Interferon gamma release assays (IGRAs) are important tools in identifying prior tuberculosis exposure. The new-generation QuantiFERON-TB Gold Plus (QFT-Plus) assay, recently approved for use in the United States, differs from the current-generation QFT Gold-In-Tube (QFT-GIT)… read more here.
Keywords: qft plus; qft; generation; qft git ... See more keywords
Preliminary performance of the VIDAS TB-IGRA as an aid in the diagnosis of individuals infected with Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01641-24
Abstract: ABSTRACT This preliminary study compares VIDAS TB-IGRA (bioMérieux, Marcy-l'Etoile, France) with the established QuantiFERON-TB Gold Plus (QFT-Plus) (Qiagen, Hilden, Germany) to evaluate diagnostic performance for the diagnosis of individuals infected with Mycobacterium tuberculosis complex (latent… read more here.
Keywords: diagnosis; qft plus; risk; tuberculosis ... See more keywords
Comparative Results of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus Assays for Detection of Tuberculosis Infection in Clinical Samples
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01854-19
Abstract: The QuantiFERON-TB Gold plus (QFT-Plus) assay, an interferon gamma (IFN-γ) release assay (IGRA), was recently introduced as the next version of the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay for diagnosing latent tuberculosis (TB). Whereas the QFT-GIT… read more here.
Keywords: qft plus; tube; quantiferon gold; qft git ... See more keywords
Fourth-Generation QuantiFERON-TB Gold Plus: What Is the Evidence?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01950-19
Abstract: QuantiFERON-TB Gold Plus (QFT-Plus) is the latest generation of interferon gamma release assays (IGRAs) to receive approval from the U.S. FDA, replacing its predecessor, QuantiFERON-TB Gold In-Tube (QFT-GIT). The novelty of QFT-Plus is that it… read more here.
Keywords: qft plus; qft git; quantiferon gold; qft ... See more keywords
SAT0157 Mycobacterium tuberculosis specific responses from CD8+ and CD4+ T cells in patients with latent and active form of tuberculosis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.5611
Abstract: Background Testing the presence of latent or active tuberculosis using IGRA tests is necessary part of the diagnostic screening at risk individuals. QuantiFERON-TB Gold Plus (QFT-Plus) is a test for cell-mediated immune (CMI) responses to… read more here.
Keywords: qft plus; latent active; levels ifn; tb1 tb2 ... See more keywords
Modulation of CD4 and CD8 response to QuantiFERON-TB-Plus in active TB patients followed during treatment
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.pa3038
Abstract: Introduction: The new IGRA called QuantiFERON-TB Plus (QFT-Plus), is based on the ELISA detection of IFNγ after stimulation with M. tuberculosis TB1 and TB2 antigens. We recently showed that while TB1 elicits mainly a CD4… read more here.
Keywords: qft plus; cd8; cd4 cd8; treatment ... See more keywords
Optimizing tuberculosis infection screening strategies for people living with HIV in Thailand: a cost-effectiveness analysis
Sign Up to like & getrecommendations! Published in 2025 at "BMC Public Health"
DOI: 10.1186/s12889-025-25491-1
Abstract: To support evidence-based decision-making in Thailand, we assessed the cost-effectiveness of QuantiFERON-TB Gold Plus (QFT-Plus) compared to the Tuberculin Skin Test (TST) in people living with HIV (PLWH). The outcomes of this investigation are intended… read more here.
Keywords: living hiv; qft plus; thailand; tuberculosis ... See more keywords
Determinants of QuantiFERON Plus-diagnosed tuberculosis infection in adult Ugandan TB contacts: A cross-sectional study
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DOI: 10.1371/journal.pone.0281559
Abstract: Background The tuberculin skin test is commonly used to diagnose latent tuberculosis infection (LTBI) in resource-limited settings, but its specificity is limited by factors including cross-reactivity with BCG vaccine and environmental mycobacteria. Interferon-gamma release assays… read more here.
Keywords: tuberculosis; qft plus; cross sectional; tuberculosis infection ... See more keywords
Intestinal Helminth Infections and Their Association with QuantiFERON-TB Gold Plus Test Performance in an Endemic Setting, Northwest Ethiopia
Sign Up to like & getrecommendations! Published in 2024 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s476492
Abstract: Background Timely detection and treatment of latent TB infection (LTBI) is part of WHO’s strategy against tuberculosis (TB). Helminth infections can modulate immune responses, potentially impacting the performance of interferon-gamma release assays (IGRAs) such as… read more here.
Keywords: qft plus; performance; infection; plus positivity ... See more keywords
Performance of T-Track® TB, a Novel Dual Marker RT-qPCR-Based Whole-Blood Test for Improved Detection of Active Tuberculosis
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13040758
Abstract: Tuberculosis (TB) is one of the leading causes of death by an infectious disease. It remains a major health burden worldwide, in part due to misdiagnosis. Therefore, improved diagnostic tests allowing the faster and more… read more here.
Keywords: blood test; qft plus; whole blood; track ... See more keywords
In Patients with Severe COVID-19, the Profound Decrease in the Peripheral Blood T-Cell Subsets Is Correlated with an Increase of QuantiFERON-TB Gold Plus Indeterminate Rates and Reflecting a Reduced Interferon-Gamma Production
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12020244
Abstract: Increased rates of indeterminate QuantiFERON-TB Gold Plus Assay (QFT-Plus) were demonstrated in patients hospitalized with Coronavirus Disease (COVID)-19. We aimed to define the prevalence and characteristics of hospitalized COVID-19 patients with indeterminate QFT-Plus. A retrospective… read more here.
Keywords: covid patients; severe covid; gold plus; qft plus ... See more keywords