Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-020-10056-x
Abstract: Doxorubicin (DOX) is an effective chemotherapy. However, its usage has been associated with adverse effects. Salidroside (SAL) is an antioxidative drug, which confers protective effects against several diseases. Salidroside can attenuate cardiac dysfunction induced by… read more here.
Keywords: attenuates doxorubicin; doxorubicin induced; qki; dysfunction ... See more keywords
QKI-V5 is downregulated in CNS inflammatory demyelinating diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2019.101881
Abstract: BACKGROUND Neuromyelitis-optica (NMO) and multiple-sclerosis (MS) are inflammatory- demyelinating-diseases of the central-nervous-system (CNS). In a previous study, we identified 17 miRNAs that were significantly upregulated in the peripheral blood of patients with NMO, relative to… read more here.
Keywords: inflammatory demyelinating; qki; demyelinating diseases; expression ... See more keywords
Abstract 1224: Quaking overexpression downregulates epithelial-mesenchymal transition in lung cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1224
Abstract: Background: Lung cancer is the leading cause of cancer death worldwide. Tumor recurrence is the most common cause of treatment failure after surgical resection. Quaking (QKI) is a functional protein that mediate alternative splicing, which… read more here.
Keywords: lung cancer; qki; overexpression; expression ... See more keywords
Promoter Methylation of QKI as a Potential Specific Biomarker for Early Detection of Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.928150
Abstract: Early and specific detection of cancer provides an opportunity for appropriate treatment. Although studies have suggested that QKI is a tumor suppressor gene, no studies have evaluated the diagnostic utility of QKI methylation in colorectal… read more here.
Keywords: methylation; qki; crc; detection ... See more keywords