Abstract 6750: QLS5132, a highly selective anti-CLDN6 ADC with broader therapeutic window
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DOI: 10.1158/1538-7445.am2025-6750
Abstract: Claudin-6 (CLDN6), a member of the claudin family, is localized in the tight junctions of epithelial cells to regulate permeability, barrier function and polarity of epithelial layers. CLDN6 is notably upregulated in multiple solid tumor… read more here.
Keywords: cancer; therapeutic window; adc; anti cldn6 ... See more keywords