Overall Survival and Quality-of-Life Superiority in Modern Phase 3 Oncology Trials: A Meta-Epidemiological Analysis.
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DOI: 10.1001/jamaoncol.2025.1002
Abstract: Importance Alternative end points, such as progression-free survival, are increasingly used in phase 3 randomized clinical trials (RCTs). However, alternative end points are often not valid surrogates for overall survival and quality of life (QOL)… read more here.
Keywords: oncology; end; qol; superiority ... See more keywords
Long-term Quality of Life After Parathyroidectomy for Primary Hyperparathyroidism: A Systematic Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA surgery"
DOI: 10.1001/jamasurg.2022.4249
Abstract: Importance Definitive treatment of primary hyperparathyroidism (pHPT) with curative parathyroidectomy has been shown to improve nonspecific neurocognitive symptoms and may improve long-term quality of life (QOL). However, QOL is not currently routinely assessed preoperatively, and… read more here.
Keywords: long term; parathyroidectomy; review; qol ... See more keywords
Hearing and quality of life in older adults.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of clinical psychology"
DOI: 10.1002/jclp.22648
Abstract: OBJECTIVES We assessed quality of life (QoL) in older adults with and without hearing loss (HL) and studied how hearing aids were associated with QoL. We hypothesized participants with normal hearing would have significantly better… read more here.
Keywords: hearing quality; qol; quality life; older adults ... See more keywords
Comparison of brachytherapy and external beam radiotherapy boost in breast-conserving therapy: Patient-reported outcome measures and aesthetic outcome
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DOI: 10.1007/s00066-018-1346-7
Abstract: ObjectiveThis study aimed to estimate the probability of an unfavourable aesthetic outcome (AO) 2 years after breast-conserving therapy (BCT) and evaluate the possible influence of brachytherapy (BT) and external beam radiotherapy (EBRT) boost on patient-reported outcomes… read more here.
Keywords: patientinnen; die; breast; boost ... See more keywords
Investigating the roles of loneliness and clinician- and self-rated depressive symptoms in predicting the subjective quality of life among people with psychosis
Sign Up to like & getrecommendations! Published in 2017 at "Social Psychiatry and Psychiatric Epidemiology"
DOI: 10.1007/s00127-017-1470-1
Abstract: PurposeTo examine the roles of loneliness and clinician- and self-rated depressive symptoms as predictors of the subjective quality of life (QoL) in psychosis.MethodsThis cross-sectional study was conducted on a sample of 207 patients diagnosed with… read more here.
Keywords: depressive symptoms; depression; roles loneliness; self rated ... See more keywords
Factors associated with the psychological quality of life among adolescents with rare diseases in China: a national repetitive cross-sectional study
Sign Up to like & getrecommendations! Published in 2022 at "Social Psychiatry and Psychiatric Epidemiology"
DOI: 10.1007/s00127-022-02286-y
Abstract: To explore the factors associated with the psychosocial quality of life (QoL) among adolescents with rare diseases (RDs). We used cross-sectional design to collect data in February 2016 and February 2018, respectively, in China through… read more here.
Keywords: qol; among adolescents; study; factors associated ... See more keywords
Quality of life of patients with osteonecrosis of the femoral head: a multicentre study
Sign Up to like & getrecommendations! Published in 2018 at "International Orthopaedics"
DOI: 10.1007/s00264-018-3897-8
Abstract: PurposeQuality-of-life (QOL) assessments in patients with osteonecrosis of the femoral head (ONFH) have rarely been reported. This multicentre study aimed to elucidate the relationship between disease severity, including necrotic lesion type and radiological staging, and… read more here.
Keywords: osteonecrosis femoral; femoral head; multicentre study; patients osteonecrosis ... See more keywords
Pruritus and sleep disturbances in patients with psoriasis
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DOI: 10.1007/s00403-019-01998-7
Abstract: Psoriasis is a prevalent skin disease that impairs multiple domains of quality of life (QoL). Pruritus, a common symptom in patients with psoriasis, may directly affect sleep, but studies investigating this are limited. We investigated… read more here.
Keywords: pruritus sleep; sleep disturbances; patients psoriasis; qol ... See more keywords
Characteristics associated with quality of life among people with drug-resistant epilepsy
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DOI: 10.1007/s00415-017-8512-1
Abstract: Quality of Life (QoL) is the preferred outcome in non-pharmacological trials, but there is little UK population evidence of QoL in epilepsy. In advance of evaluating an epilepsy self-management course we aimed to describe, among… read more here.
Keywords: epilepsy; associated quality; quality life; qol ... See more keywords
Apathy and its impact on patient outcome in amyotrophic lateral sclerosis
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DOI: 10.1007/s00415-017-8688-4
Abstract: Apathy is one of the most common behavioural symptoms of amyotrophic lateral sclerosis (ALS), yet there are few studies that have investigated the relationship between apathy and quality of life (QOL) as they are experienced… read more here.
Keywords: apathy impact; amyotrophic lateral; als patients; qol ... See more keywords
Do pain, anxiety and depression influence quality of life for people with amyotrophic lateral sclerosis/motor neuron disease? A national study reconciling previous conflicting literature
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09615-3
Abstract: Introduction The importance of elucidating the relationships between pain, mood and quality of life (QoL) amongst people with amyotrophic lateral sclerosis/motor neuron disease is evident to clinicians, yet the literature is limited and inconsistent. We… read more here.
Keywords: depression; anxiety; quality life; qol ... See more keywords