Design, synthesis, cytotoxicity and 3D-QSAR analysis of new 3,6-disubstituted-1,2,4,5-tetrazine derivatives as potential antitumor agents
Sign Up to like & getrecommendations! Published in 2019 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2017.04.002
Abstract: Abstract We synthesized two new series of 3-substituted-6-(2,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazines and analysed them for a potential role as antitumor agents. Twenty-two compounds were obtained, and four molecular structures were determined by X-ray diffraction analysis. Using flow cytometry… read more here.
Keywords: tetrazine derivatives; qsar analysis; cell; analysis ... See more keywords
Green synthesis, antibacterial evaluation and QSAR analysis of some isatin Schiff bases
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DOI: 10.1016/j.molstruc.2020.127853
Abstract: Abstract Twelve isatin Schiff bases (1a-7a, 1b-5b) were prepared by reacting isatin and 5-bromoisatin with different anilines using green chemistry (microwave (MW) and ultrasound (US) assisted synthesis). The antibacterial activity of each compound was evaluated… read more here.
Keywords: schiff bases; isatin; synthesis antibacterial; qsar analysis ... See more keywords
Quantitative Structure-Activity Relationship (QSAR) analysis of functionalized triblock copolymers with applications as dehydrating agents of crude oil
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DOI: 10.1080/01932691.2019.1611439
Abstract: Abstract QSAR analysis was applied to obtain the water removal efficiency (WRE) values of triblock copolymers functionalized with tertiary amines, employed as demulsifier agents of crude oil. Taking into account the evaluation of F- and… read more here.
Keywords: qsar analysis; crude oil; oil; triblock copolymers ... See more keywords
Design, synthesis, biological evaluation and QSAR analysis of novel N-substituted benzimidazole derived carboxamides
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DOI: 10.1080/14756366.2022.2070910
Abstract: Abstract As a result of our previous research focussed on benzimidazoles, herein we present design, synthesis, QSAR analysis and biological activity of novel N-substituted benzimidazole derived carboxamides. Carboxamides were designed to study the influence of… read more here.
Keywords: design synthesis; qsar analysis; benzimidazole derived; novel substituted ... See more keywords
QSAR analysis of immune recognition for triazine herbicides based on immunoassay data for polyclonal and monoclonal antibodies
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DOI: 10.1371/journal.pone.0214879
Abstract: A common task in the immunodetection of structurally close compounds is to analyze the selectivity of immune recognition; it is required to understand the regularities of immune recognition and to elucidate the basic structural elements… read more here.
Keywords: analysis immune; qsar analysis; monoclonal antibodies; immune recognition ... See more keywords