Flavonoids as BACE1 inhibitors: QSAR modelling, screening and in vitro evaluation.
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DOI: 10.1016/j.ijbiomac.2020.09.232
Abstract: Alzheimer's disease (AD) is marked by the presence of amyloid plaques, neurofibrillary tangles, oxidatively damaged neuronal macromolecules and redox sensitive ions. Reduction of amyloid plaques and oxidative stress emerge as a convincing treatment strategy. Plaque… read more here.
Keywords: bace1 inhibitors; modelling screening; flavonoids bace1; inhibitors qsar ... See more keywords