Improving the generation and selection of virtual populations in quantitative systems pharmacology models.
Sign Up to like & getrecommendations! Published in 2018 at "Progress in biophysics and molecular biology"
DOI: 10.1016/j.pbiomolbio.2018.06.002
Abstract: Quantitative systems pharmacology (QSP) models aim to describe mechanistically the pathophysiology of disease and predict the effects of therapies on that disease. For most drug development applications, it is important to predict not only the… read more here.
Keywords: qsp models; systems pharmacology; pharmacology; improving generation ... See more keywords
A Review of Quantitative Systems Pharmacology Models of the Coagulation Cascade: Opportunities for Improved Usability
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15030918
Abstract: Despite the numerous therapeutic options to treat bleeding or thrombosis, a comprehensive quantitative mechanistic understanding of the effects of these and potential novel therapies is lacking. Recently, the quality of quantitative systems pharmacology (QSP) models… read more here.
Keywords: coagulation; systems pharmacology; pharmacology; quantitative systems ... See more keywords