Enhancing discoveries of molecular QTL studies with small sample size using summary statistic imputation.
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbab370
Abstract: Quantitative trait locus (QTL) analyses of multiomic molecular traits, such as gene transcription (eQTL), DNA methylation (mQTL) and histone modification (haQTL), have been widely used to infer the functional effects of genome variants. However, the… read more here.
Keywords: qtl studies; imputation; studies small; molecular qtl ... See more keywords
Fifteen years of quantitative trait loci studies in fish: challenges and future directions
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Ecology"
DOI: 10.1111/mec.13965
Abstract: Understanding the genetic basis of phenotypic variation is a major challenge in biology. Here, we systematically evaluate 146 quantitative trait loci (QTL) studies on teleost fish over the last 15 years to investigate (i) temporal… read more here.
Keywords: fifteen years; qtl studies; quantitative trait; trait loci ... See more keywords