Radiobiology of brachytherapy: The historical view based on linear quadratic model and perspectives for optimization.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique"
DOI: 10.1016/j.canrad.2017.11.011
Abstract: Most preclinical studies examining the radiobiology of brachytherapy have focused on dose rate effects. Scarcer data are available on other major parameters of therapeutic index, such as cell cycle distribution, repopulation or reoxygenation. The linear… read more here.
Keywords: brachytherapy historical; radiobiology brachytherapy; linear quadratic; radiobiology ... See more keywords
The invalidity of and Alternative to Linear Quadratic Model as a Predictive Model for Post-Irradiation Cell Survival.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer science"
DOI: 10.1111/cas.15796
Abstract: The linear-quadratic (LQ) model has been the dominant tool in preclinical radiobiological modeling of cell survival as a function of dose. However, as a second-order polynomial approximation, it suffers from two well-known pitfalls: non-monotonic behavior… read more here.
Keywords: cross validation; linear quadratic; model; cell survival ... See more keywords
Development and Optimization of Methylcellulose-Based Nanoemulgel Loaded with Nigella sativa Oil for Oral Health Management: Quadratic Model Approach
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DOI: 10.3390/molecules27061796
Abstract: The present study aimed to develop a local dental nanoemulgel formulation of Nigella sativa oil (NSO) for the treatment of periodontal diseases. NSO purchased from a local market was characterized using a GC–MS technique. A… read more here.
Keywords: formulation; sativa oil; nigella sativa; quadratic model ... See more keywords