Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults.
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DOI: 10.1001/jamaneurol.2020.1741
Abstract: Importance Quadruple misfolded proteins (tau neurofibrillary tangles, amyloid-β [Aβ], α-synuclein, and transactive response DNA-binding protein 43 [TDP-43]) in the same brain are relatively common in aging. However, the clinical presentation, associated factors, frequency in community-based… read more here.
Keywords: death; misfolded proteins; quadruple misfolded; disease ... See more keywords