Quadruplex Folding Promotes the Condensation of Linker Histones and DNAs via Liquid-Liquid Phase Separation.
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DOI: 10.1021/jacs.1c03447
Abstract: Liquid-liquid phase separation (LLPS) of proteins and DNA has recently emerged as a possible mechanism underlying the dynamic organization of chromatin. We herein report the role of DNA quadruplex folding in liquid droplet formation via… read more here.
Keywords: liquid; liquid phase; quadruplex folding; dna ... See more keywords
Effects of monovalent cations on folding kinetics of G-quadruplexes
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DOI: 10.1042/bsr20170771
Abstract: G-quadruplexes are special structures existing at the ends of human telomeres, the folding kinetics of which are essential for their functions, such as in the maintenance of genome stability and the protection of chromosome ends.… read more here.
Keywords: induced quadruplexes; effects monovalent; quadruplex folding; cations folding ... See more keywords
Tracking Topological and Electronic Effects on the Folding and Stability of Guanine-Deficient RNA G-Quadruplexes, Engineered with a New Computational Tool for De Novo Quadruplex Folding
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DOI: 10.3390/ijms231910990
Abstract: The initial aim of this work was to elucidate the mutual influence of different single-stranded segments (loops and caps) on the thermodynamic stability of RNA G-quadruplexes. To this end, we used a new NAB-GQ-builder software… read more here.
Keywords: tracking topological; rna quadruplexes; quadruplex folding; stability ... See more keywords