Split G-quadruplex-programmed label-free CRISPR-Cas12a sensing system.
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DOI: 10.1039/d3cc01239e
Abstract: A split G-quadruplex (G4)-programmed Cas12a platform was established, validated, and optimized. The split G4 motif was recruited as substrate for Cas12a, and the label-free sensing platform provided a concentration-dependent response towards the input target. Furthermore,… read more here.
Keywords: programmed label; label free; split quadruplex; cas12a ... See more keywords