Enantiomeric separation and quantification of R/S-amphetamine in serum using semi-automated liquid-liquid extraction and ultra-high performance supercritical fluid chromatography-tandem mass spectrometry.
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DOI: 10.1002/dta.2879
Abstract: The amphetamine molecule contains a chiral center and its enantiomers exhibit differences in pharmacological effects, with the S-enantiomer mediating most of the central nervous system stimulating activity. The majority of prescribed amphetamine consists of the… read more here.
Keywords: quantification amphetamine; enantiomeric separation; amphetamine; separation quantification ... See more keywords