Potential application of mass spectrometry imaging in pharmacokinetic studies
Sign Up to like & getrecommendations! Published in 2022 at "Xenobiotica"
DOI: 10.1080/00498254.2022.2119900
Abstract: Abstract Although liquid chromatography-tandem mass spectrometry is the gold standard analytical platform for the quantification of drugs, metabolites, and biomarkers in biological samples, it cannot localise them in target tissues. The localisation and quantification of… read more here.
Keywords: spectrometry imaging; mass spectrometry; pharmacokinetic studies; spectrometry ... See more keywords
Challenges and Strategies for Quantification of Drugs in the Brain: Current Scenario and Future Advancement.
Sign Up to like & getrecommendations! Published in 2020 at "Critical reviews in analytical chemistry"
DOI: 10.1080/10408347.2020.1791041
Abstract: The site of action of centrally acting drugs lies inside the brain and therefore, needs to reach the brain to exert their therapeutic efficacy. Discovery and development process of such types of drugs demands their… read more here.
Keywords: strategies quantification; quantification drugs; inside brain; drugs brain ... See more keywords