Quantification of microdosed oral yohimbine and its major metabolite in human plasma in the picogram range.
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DOI: 10.4155/bio-2019-0129
Abstract: Aim: Pharmacokinetics after oral microdosing of the anticipated CYP2D6 substrate yohimbine and its metabolite 11-OH-yohimbine is potentially useful for drug-drug interaction trials and profiling of CYP2D6 enzyme activity. Materials & methods: We developed an ultrasensitive… read more here.
Keywords: plasma; range; microdosed oral; quantification microdosed ... See more keywords