Quantification of oxalate by novel LC-MS/MS: assay development, validation and application in lumasiran clinical trials.
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DOI: 10.4155/bio-2022-0227
Abstract: Background: Measurement of plasma oxalate (POx) is challenging, but critical, for management of patients with primary hyperoxaluria type 1. A novel LC-MS/MS assay was developed, validated and used to quantify POx in patients with primary hyperoxaluria… read more here.
Keywords: development validation; quantification oxalate; quantification; novel assay ... See more keywords