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Published in 2022 at "Bioanalysis"
DOI: 10.4155/bio-2021-0246
Abstract: Aim: HCP002, a phosphate-modified derivative of voriconazole, can improve solubility without using the nephrotoxic solubilizer, sulfobutylether-β-cyclodextrin. To study pharmacokinetics in humans, LC-MS/MS methods to quantify HCP002 in human plasma and urine were developed and validated.…
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Keywords:
plasma urine;
hcp002 human;
plasma;
methods quantify ... See more keywords