Population PBPK modelling of trastuzumab: a framework for quantifying and predicting inter-individual variability
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DOI: 10.1007/s10928-017-9515-3
Abstract: In this work we proposed a population physiologically-based pharmacokinetic (popPBPK) framework for quantifying and predicting inter-individual pharmacokinetic variability using the anti-HER2 monoclonal antibody (mAb) trastuzumab as an example. First, a PBPK model was developed to… read more here.
Keywords: variability; inter individual; quantifying predicting; framework quantifying ... See more keywords