Precise Quantitation of PTEN by Immuno-MRM: A Tool To Resolve the Breast Cancer Biomarker Controversy.
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DOI: 10.1021/acs.analchem.1c00975
Abstract: The tumor suppressor PTEN is the main negative regulator of PI3K/AKT/mTOR signaling and is commonly found downregulated in breast cancer (BC). Conflicting data from conventional immunoassays such as immunohistochemistry (IHC) has sparked controversy about PTEN's… read more here.
Keywords: quantitation pten; mrm; biomarker; breast cancer ... See more keywords