Articles with "quantitation scarce" as a keyword



Photo by bermixstudio from unsplash

Synthetic Glycopeptides Allow for the Quantitation of Scarce Nonfucosylated IgG Fc N-Glycans of Therapeutic Antibody.

Sign Up to like & get
recommendations!
Published in 2018 at "ACS medicinal chemistry letters"

DOI: 10.1021/acsmedchemlett.8b00127

Abstract: Glycans attached to the IgG Fc domain affect strongly biological activities such as antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) of therapeutic antibodies. However, molecular mechanism in the glycoform-dependent functional modulation of the IgGs… read more here.

Keywords: quantitation scarce; glycopeptides allow; igg glycans; antibody ... See more keywords