Computationally efficient whole-genome regression for quantitative and binary traits.
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DOI: 10.1038/s41588-021-00870-7
Abstract: Genome-wide association analysis of cohorts with thousands of phenotypes is computationally expensive, particularly when accounting for sample relatedness or population structure. Here we present a novel machine-learning method called REGENIE for fitting a whole-genome regression… read more here.
Keywords: whole genome; regression; efficient whole; computationally efficient ... See more keywords