A shrinkage-based statistical method for testing group mean differences in quantitative bottom-up proteomics
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DOI: 10.1186/s12859-025-06275-1
Abstract: In bottom-up proteomics using data-independent acquisition mass spectrometry (DIA-MS), quantitative measurements are obtained following multiple steps of protein fragmentation and ionization, which introduces cumulative errors and impairs the effectiveness of classical statistical methods. This study… read more here.
Keywords: method; testing group; statistical method; quantitative bottom ... See more keywords