Light‐Wavelength‐Based Quantitative Control of Dihydrofolate Reductase Activity by Using a Photochromic Isostere of an Inhibitor
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DOI: 10.1002/cbic.201800816
Abstract: Photopharmacology has attracted research attention as a new tool for achieving optical control of biomolecules, following the methods of caged compounds and optogenetics. We have developed an efficient photopharmacological inhibitor—azoMTX—for Escherichia coli dihydrofolate reductase (eDHFR)… read more here.
Keywords: inhibitor; dihydrofolate reductase; control; activity ... See more keywords
Qualitative and quantitative control of pediatric syrups using Nuclear Magnetic Resonance and chemometrics
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DOI: 10.1016/j.jpba.2018.02.013
Abstract: Graphical abstract Figure. No Caption available. HighlightsThe 1H NMR was applied to qualitative and quantitative analyses of pediatric syrup.This approach allows identifying several added compounds.Some syrups presented both sugar and sweeteners, and high ethanol content.The… read more here.
Keywords: control pediatric; syrups using; qualitative quantitative; added compounds ... See more keywords
Quantitative control of mitochondria transfer between live single cells using a microfluidic device
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DOI: 10.1242/bio.024869
Abstract: ABSTRACT Quantitative control of mitochondria transfer between live cells is a promising approach for genetic manipulation of mitochondrial DNA (mtDNA) because single mitochondrion transfer to a mtDNA-less (ρ0) cell potentially leads to homoplasmy of mtDNA.… read more here.
Keywords: control mitochondria; transfer live; transfer; mitochondria transfer ... See more keywords