Isolation of Proteins on Nascent Chromatin and Characterization by Quantitative Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9434-2_2
Abstract: Replication-coupled chromatin assembly is a very dynamic process that involves not only the replication fork machinery but also chromatin-related factors such as histones, histone chaperones, histone-modifying enzymes, and chromatin remodelers which ensure not only that… read more here.
Keywords: chromatin; quantitative mass; mass spectrometry; isolation proteins ... See more keywords
Tumor Distribution by Quantitative Mass Spectrometry Imaging of the Inhibitor of Apoptosis Protein Antagonist Xevinapant in Patients with Resectable Squamous Cell Carcinoma of the Head and Neck (EudraCT Number: 2014-004655-31).
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00943
Abstract: As tumors are very heterogeneous, investigating the penetration and concentration of an anticancer drug in different histological regions of a tumor is key to evaluate the efficacy, to improve the pharmacokinetics/pharmacodynamics (PK/PD) relationship evaluation, and… read more here.
Keywords: spectrometry imaging; inhibitor apoptosis; mass spectrometry; quantitative mass ... See more keywords
Virtual Calibration Quantitative Mass Spectrometry Imaging for Accurately Mapping Analytes across Heterogenous Biotissue.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b04762
Abstract: It is highly challenging to quantitatively map multiple analytes in biotissues without specific chemical labeling. Quantitative mass spectrometry imaging (QMSI) has this potential but still poses technical issues for its variant ionization efficiency across a… read more here.
Keywords: spectrometry imaging; virtual calibration; quantitative mass; mass spectrometry ... See more keywords
Quantitative mass spectrometry of human reticulocytes reveal proteome‐wide modifications during maturation
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Haematology"
DOI: 10.1111/bjh.14976
Abstract: Erythropoiesis is marked by progressive changes in morphological, biochemical and mechanical properties of erythroid precursors to generate red blood cells (RBC). The earliest enucleated forms derived in this process, known as reticulocytes, are multi‐lobular and… read more here.
Keywords: spectrometry human; proteome wide; quantitative mass; mass spectrometry ... See more keywords
Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17261
Abstract: Cruciferous vegetables such as broccoli and kale have well documented chemopreventative and anticancer effects that are attributed to the presence of isothiocyanates (ITCs). ITCs modulate the levels of many oncogenic proteins, but the molecular mechanisms… read more here.
Keywords: assisted quantitative; mass spectrometry; using silac; silac assisted ... See more keywords
Direct Identification of Functional Amyloid Proteins by Label-Free Quantitative Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2017 at "Biomolecules"
DOI: 10.3390/biom7030058
Abstract: Functional amyloids are important structural and functional components of many biofilms, yet our knowledge of these fascinating polymers is limited to a few examples for which the native amyloids have been isolated in pure form.… read more here.
Keywords: functional amyloid; amyloid; free quantitative; amyloid proteins ... See more keywords