Quantitative IR microscopy and spectromics open the way to 3D digital pathology.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600051
Abstract: Currently, only mass-spectrometry (MS) microscopy brings a quantitative analysis of chemical contents of tissue samples in 3D. Here, the reconstruction of a 3D quantitative chemical images of a biological tissue by FTIR spectro-microscopy is reported.… read more here.
Keywords: microscopy spectromics; microscopy; pathology; tissue ... See more keywords
Quantitative microscopy based on single-molecule fluorescence.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2017.06.004
Abstract: Quantitative microscopy is needed to understand reactions or phenomena carried out by biological molecules such as enzymes, receptors, and membrane-localized proteins. Counting the biomolecules of interest in single organelles or cellular compartments is critical in… read more here.
Keywords: single molecule; fluorescence; microscopy; microscopy based ... See more keywords
Quantitative microscopy uncovers ploidy changes during mitosis in live Drosophila embryos and their effect on nuclear size
Sign Up to like & getrecommendations! Published in 2017 at "Biology Open"
DOI: 10.1242/bio.022079
Abstract: ABSTRACT Time-lapse microscopy is a powerful tool to investigate cellular and developmental dynamics. In Drosophila melanogaster, it can be used to study division cycles in embryogenesis. To obtain quantitative information from 3D time-lapse data and… read more here.
Keywords: microscopy; drosophila embryos; size; quantitative microscopy ... See more keywords