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Published in 2019 at "PROTEOMICS"
DOI: 10.1002/pmic.201900057
Abstract: Oligodendrocytes, the myelinating cells of the central nervous system, are essential for correct brain function. They originate from oligodendrocyte precursor cells through a differentiation process which is only incompletely understood and impaired in a variety…
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Keywords:
differentiation;
quantitative proteomics;
cell;
oligodendrocyte precursor ... See more keywords
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Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0528-8_10
Abstract: Dimethyl labeling is a type of stable-isotope labeling suitable for creating isotopic variants of peptides and thus be utilized for quantitative proteomics experiments. Labeling is achieved through a reductive amination/alkylation reaction using the low-cost reagents…
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Keywords:
dimethyl labeling;
isotopic variants;
quantitative proteomics;
cocoa pod ... See more keywords
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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1024-4_4
Abstract: Two-dimensional gel electrophoresis has been instrumental in the development of proteomics. Although it is no longer the exclusive scheme used for proteomics, its unique features make it a still highly valuable tool, especially when multiple…
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Keywords:
two dimensional;
quantitative proteomics;
biology;
gels quantitative ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8784-9_13
Abstract: Xenopus oocytes and embryos are model systems optimally suited for quantitative proteomics. This is due to the availability of large amount of protein material and the ease of physical manipulation. Furthermore, facile in vitro fertilization…
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Keywords:
xenopus embryos;
proteomics xenopus;
sample preparation;
quantitative proteomics ... See more keywords
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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9232-4_12
Abstract: Metabolites and proteins are potential biomarkers. They can be identified with the help of mass spectrometry (MS). However, measurements obtained by using MS are prone to various random and systematic errors. The sensitivity of the…
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Keywords:
design quantitative;
experimental design;
quantitative proteomics;
biology ... See more keywords
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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9232-4_5
Abstract: Lysine acetylation is an important posttranslational modification (PTM) that regulates the function of proteins by affecting their localization, stability, binding, and enzymatic activity. Aberrant acetylation patterns have been observed in numerous diseases, most notably cancer,…
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Keywords:
labeling quantitative;
acetylation;
acetylation histones;
proteomics acetylation ... See more keywords
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Published in 2018 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-018-0958-1
Abstract: ObjectiveMolecular pathogenesis of parathyroid tumors is incompletely understood. Identification of novel molecules and understanding their role in parathyroid tumorigenesis by proteomics approach would be informative with potential clinical implications.MethodAdenomatous (n = 5) and normal (n = 2) parathyroid tissue…
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Keywords:
analysis sporadic;
analysis;
parathyroid;
tissue ... See more keywords
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Published in 2021 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2021.109465
Abstract: Zingiberis Rhizome Carbonisata (ZRC) has been used as a hemostatic agent in traditional Chinese medicine (TCM). However, the underlying molecular mechanism remains unclear. In this study, network pharmacology method was used to predict the potential…
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Keywords:
mechanism;
zingiberis rhizome;
pharmacology;
network pharmacology ... See more keywords
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Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.10.107
Abstract: Human multipotent stromal cells (hMSCs) are one of the most versatile cell types used in regenerative medicine due to their ability to respond to injury. In the context of diabetes, it has been previously shown that…
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Keywords:
multipotent stromal;
human multipotent;
cell;
quantitative proteomics ... See more keywords
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Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.01.160
Abstract: Recently, studies on human salt taste sensitivity demonstrated that sodium chloride (NaCl) sensitive and non-sensitive subjects differed in their salivary proteome and, in particular, in endopeptidase activity. In order to investigate individual's NaCl sensitivity and…
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Keywords:
taste;
taste sensitivity;
sensitivity;
quantitative proteomics ... See more keywords
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Published in 2022 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2022.128709
Abstract: With the increasing concerns regarding bacterial adaption to nanomaterials, it is critical to explore the main mechanism behind the adaptive morphogenesis of microorganisms. In this work, the biofilms formed from activated sludge exposed to 5…
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Keywords:
quantitative proteomics;
biofilm formation;
biofilm;
mechanism ... See more keywords