Quantitative Visualization of the Interaction between Complement Component C1 and Immunoglobulin G: The Effect of CH1 Domain Deletion
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DOI: 10.3390/ijms23042090
Abstract: Immunoglobulin G (IgG) adopts a modular multidomain structure that mediates antigen recognition and effector functions, such as complement-dependent cytotoxicity. IgG molecules are self-assembled into a hexameric ring on antigen-containing membranes, recruiting the complement component C1q.… read more here.
Keywords: ch1 domain; quantitative visualization; domain; interaction ... See more keywords