A convergent fragment coupling strategy to access quaternary stereogenic centers
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d2sc07023e
Abstract: The formation of quaternary stereogenic centers via convergent fragment coupling is a longstanding challenge in organic synthesis. Here, we report a strategy for the formation of quaternary stereogenic centers in polycyclic systems based upon the… read more here.
Keywords: convergent fragment; stereogenic centers; coupling strategy; quaternary stereogenic ... See more keywords
H-Bond Mediated Phase-Transfer Catalysis: Enantioselective Generating of Quaternary Stereogenic Centers in β-Keto Esters
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27082508
Abstract: In this work, we would like to present the development of a highly optimized method for generating the quaternary stereogenic centers in β-keto esters. This enantioselective phase-transfer alkylation catalyzed by hybrid Cinchona catalysts allows for… read more here.
Keywords: phase transfer; generating quaternary; quaternary stereogenic; stereogenic centers ... See more keywords