Synthesis and antioxidant properties of (dodecylsulfanyl)methyl quercetin derivatives
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DOI: 10.1007/s11172-019-2701-2
Abstract: Mono-, bis-, and tris[(dodecylsulfanyl)methyl]-substituted quercetin derivatives were obtained by the reaction of quercetin with (N,N-diethylaminomethyl) dodecyl sulfide. These compounds under the conditions of AIBN-initiated oxidation of styrene (37 °C) terminated oxidation chains with a stoichiometric… read more here.
Keywords: antioxidant properties; properties dodecylsulfanyl; dodecylsulfanyl methyl; synthesis antioxidant ... See more keywords
Synthesis of 8-aryl-3,5,7,3′,4′-penta-O-methylcyanidins from the corresponding quercetin derivatives by reduction with LiAlH4
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DOI: 10.1016/j.tetlet.2017.01.065
Abstract: Synthesis of 8-aryl-3,5,7,3′,4′-penta-O-methylcyanidins from the corresponding quercetin derivatives by reduction with LiAlH4 is reported. Regioselective iodination at the 8-position of penta-O-methylquercetin followed by a Suzuki-Miyaura reaction gave the 8-arylated quercetin derivatives. By the reduction of… read more here.
Keywords: derivatives reduction; aryl penta; quercetin derivatives; synthesis aryl ... See more keywords
Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives
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DOI: 10.1038/s41598-019-55654-1
Abstract: Mammalian Sirtuin 6 (Sirt6) is an NAD+-dependent protein deacylase regulating metabolism and chromatin homeostasis. Sirt6 activation protects against metabolic and aging-related diseases, and Sirt6 inhibition is considered a cancer therapy. Available Sirt6 modulators show insufficient… read more here.
Keywords: structural basis; sirtuin; site; quercetin ... See more keywords
Quercetin Derivatives in Combating Spinal Cord Injury: A Mechanistic and Systematic Review
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DOI: 10.3390/life12121960
Abstract: Spinal cord injury (SCI) possesses a complicated etiology. There is no FDA-approved treatment for SCI, and the majority of current interventions focus on reducing symptoms. During SCI, inflammation, oxidative stress, apoptosis, and autophagy are behind… read more here.
Keywords: systematic review; cord injury; quercetin derivatives; spinal cord ... See more keywords
Changes in Quercetin Derivatives and Antioxidant Activity in Marigold Petals (Tagetes patula L.) Induced by Ultraviolet-B Irradiation and Methyl Jasmonate
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DOI: 10.3390/plants11212947
Abstract: Marigold petals contain numerous antioxidative flavonoids and carotenoids that can be affected by environmental stressors. There is yet no detailed study on the relationship between phytochemical accumulation and stressors in marigold petals. This study evaluated… read more here.
Keywords: quercetin derivatives; antioxidant activity; marigold petals; treatment ... See more keywords