UHPLC-MS/MS assay using environment friendly organic solvents: A green approach for fast determination of quetiapine in rat plasma
Sign Up to like & getrecommendations! Published in 2019 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2014.11.039
Abstract: Abstract Reduction or elimination of traditional hazardous chemicals in chromatographic separation and sample preparation is comparatively safer and can be considered as a greener approach for the determination of analytes in biological matrices. A rapid… read more here.
Keywords: quetiapine; approach; organic solvents; determination ... See more keywords
A different insight in hair analysis: Simultaneous measurement of antipsychotic drugs and metabolites in the protein and melanin fraction of hair from criminal justice patients.
Sign Up to like & getrecommendations! Published in 2020 at "Forensic science international"
DOI: 10.1016/j.forsciint.2020.110337
Abstract: BACKGROUND Previous studies have postulated that four structural compartments may be differentiated in hair: surface protein domain, water-accessible protein domain, water-inaccessible protein domain, and melanin. Drugs contained in blood, sweat, sebum, and environment would be… read more here.
Keywords: protein; melanin; hair; loq ... See more keywords
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.06.005
Abstract: Quetiapine is a common atypical antipsychotic used to treat mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. There has been increasing number of reports describing its cardiotoxicity. However, the molecular mechanisms underlying… read more here.
Keywords: quetiapine; quetiapine induced; cannabinoid receptors; cell death ... See more keywords
Application of a glassy carbon electrode modified with carbon black nanoparticles for highly sensitive voltammetric determination of quetiapine
Sign Up to like & getrecommendations! Published in 2017 at "Analytical Methods"
DOI: 10.1039/c7ay02140b
Abstract: A novel highly sensitive voltammetric quetiapine fumarate (QF) sensor based on a glassy carbon electrode (GCE) modified with carbon black nanoparticles (CB) was successfully developed. The electrochemical behaviour of the modified electrode and electrooxidation of… read more here.
Keywords: glassy carbon; carbon; sensitive voltammetric; highly sensitive ... See more keywords
Quetiapine abuse and dependence: is pharmacokinetics important?
Sign Up to like & getrecommendations! Published in 2018 at "Acta Clinica Belgica"
DOI: 10.1080/17843286.2017.1339964
Abstract: I read with interest the paper by Cornelis et al. [1], addressing the issue of quetiapine abuse in persistent insomnia disorder. The authors described an interesting case of dependence developing in course of the treatment… read more here.
Keywords: quetiapine abuse; abuse dependence; drug; quetiapine ... See more keywords
Adjunctive quetiapine may help fluvoxamine-resistant obsessive-compulsive disorder among female in-patients: A randomized-controlled study
Sign Up to like & getrecommendations! Published in 2019 at "Psychiatry and Clinical Psychopharmacology"
DOI: 10.1080/24750573.2019.1597584
Abstract: ABSTRACT INTRODUCTION: while around half of the patients with obsessive-compulsive disorder do not respond efficiently to current serotonin-reuptake inhibitors, the objective of the present study was to compare the effectiveness and safety of quetiapine versus… read more here.
Keywords: compulsive disorder; obsessive compulsive; patients obsessive; resistant obsessive ... See more keywords
Neurofunctional Correlates of Response to Quetiapine in Adolescents with Bipolar Depression.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of child and adolescent psychopharmacology"
DOI: 10.1089/cap.2017.0030
Abstract: OBJECTIVES Prior studies have shown that youth with bipolar disorder demonstrate neurofunctional changes in key prefrontal and subcortical brain regions implicated in emotional regulation following treatment with pharmacological agents. We recently reported a large response… read more here.
Keywords: depression; response; bipolar depression; adolescents bipolar ... See more keywords
Neutropenia in Incarcerated Adolescents Secondary to Intranasal Quetiapine Misuse.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of child and adolescent psychopharmacology"
DOI: 10.1089/cap.2020.0118
Abstract: Objective: Between April 2015 and May 2016, a number of young males incarcerated at a Youth Justice center in New South Wales, Australia, were noted to have unexplained and significant neutropenia. None of the adolescents… read more here.
Keywords: quetiapine misuse; center; quetiapine; young people ... See more keywords
Reproductive Safety of Lurasidone and Quetiapine: Update from the National Pregnancy Registry for Psychiatric Medications.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of women's health"
DOI: 10.1089/jwh.2022.0310
Abstract: Background: Second-generation antipsychotics (SGAs), also called atypical antipsychotics, are common therapies for women with a spectrum of psychiatric disorders. No systematically ascertained human reproductive safety data are available for lurasidone, and prospective data for quetiapine… read more here.
Keywords: quetiapine; reproductive safety; lurasidone quetiapine; pregnancy ... See more keywords
Effect of N-Desalkylquetiapine/Quetiapine Plasma Level Ratio on Anxiety and Depression in Bipolar Disorder: A Prospective Observational Study.
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutic drug monitoring"
DOI: 10.1097/ftd.0000000000000413
Abstract: BACKGROUND The aim of this study was to analyze the relationships between quetiapine and N-desalkylquetiapine plasma levels and clinical improvement, particularly, in regard to depressive and anxious symptoms and to hostility. METHODS This was a… read more here.
Keywords: desalkylquetiapine quetiapine; anxiety; study; ratio ... See more keywords
Massive Creatine Kinase Elevation in 2 Patients During Short-Term and Low-Dose Antipsychotic Monotherapy With Quetiapine.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Psychopharmacology"
DOI: 10.1097/jcp.0000000000000902
Abstract: To the Editors: Q uetiapine is recommended for the psychopharmacological treatment of a broad range of psychiatric disorders. Currently, quetiapine is the most commonly prescribed atypical antipsychotic with around 55 million daily doses per year… read more here.
Keywords: low dose; treatment; kinase elevation; elevation ... See more keywords