Role of butter oil in brain targeted delivery of Quetiapine fumarate microemulsion via intranasal route
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2017.05.004
Abstract: Abstract Purpose of the present investigation was to explore the potential of butter oil (BO) as a novel permeation enhancer to enhance the drug concentration in the brain when given intranasally. Quetiapine fumarate (QF) was… read more here.
Keywords: butter oil; delivery; brain; quetiapine fumarate ... See more keywords
Influence of Plasdone™ S630 Ultra-an Improved Copovidone on the Processability and Oxidative Degradation of Quetiapine Fumarate Amorphous Solid Dispersions Prepared via Hot-Melt Extrusion Technique.
Sign Up to like & getrecommendations! Published in 2021 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-021-02069-9
Abstract: In a formulation, traces of peroxides in copovidone can impact the stability of drug substances that are prone to oxidation. The present study aimed to investigate the impact of peroxides in novel Plasdone™ S630 Ultra… read more here.
Keywords: plasdone s630; s630; s630 ultra; oxidative degradation ... See more keywords
Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15080940
Abstract: This study aimed to formulate and statistically optimize glycerosomal formulations of Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery. The study was designed using a Central composite rotatable design using… read more here.
Keywords: oral bioavailability; quetiapine fumarate; brain; bioavailability ... See more keywords
Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment
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DOI: 10.3390/ph15091083
Abstract: A liposphere system for intranasal delivery of quetiapine fumarate (QTF) was created to assess the potential for enhanced drug delivery. We investigated the effects of particle size, entrapment effectiveness, poly dispersibility index, and pluronic incorporation… read more here.
Keywords: intranasal delivery; quetiapine fumarate; brain; loaded lipospheres ... See more keywords
Effect of Polymers and Permeation Enhancers in the Release of Quetiapine Fumarate Transdermal Patch through the Dialysis Membrane
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DOI: 10.3390/polym14101984
Abstract: Quetiapine Fumarate is potent, and the daily therapeutic dose can be delivered easily across the skin with the help of permeation enhancers. Quetiapine Fumarate-loaded transdermal patches were prepared by solvent evaporation technique. Various formulation parameters,… read more here.
Keywords: fumarate transdermal; quetiapine fumarate; transdermal patch; fumarate ... See more keywords