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Quetiapine Shortens the Lifespan of Caenorhabditis elegans through DOP-2, DAF-2 and RSKS-1

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2 Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232112927

Abstract: Recent studies implicate a key role of dopamine signaling in lifespan regulation. Our previous study found that quetiapine, an atypical antipsychotic drug that has antagonistic activity on dopamine D2-like receptors (D2Rs), shortened the lifespan of… read more here.

Keywords: effect; caenorhabditis elegans; lifespan caenorhabditis; quetiapine shortens ... See more keywords