AKT1low quiescent cancer cells in ductal carcinoma in situ of the breast
Sign Up to like & getrecommendations! Published in 2019 at "NPJ Breast Cancer"
DOI: 10.1038/s41523-019-0105-y
Abstract: Ductal carcinoma in situ (DCIS) of the breast precedes the development of invasive breast cancer and reflects the genomic changes and protein expression profile of invasive disease. AKT1low cancer cells (QCC) are a rare, drug-tolerant,… read more here.
Keywords: carcinoma situ; breast; quiescent cancer; ductal carcinoma ... See more keywords
Ablation of p57+ Quiescent Cancer Stem Cells Suppresses Recurrence After Chemotherapy of Intestinal Tumors.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-2578
Abstract: Quiescent cancer stem cells (CSCs) are resistant to conventional anti-cancer treatments and have been shown to contribute to disease relapse after therapy in some cancer types. The identification and characterization of quiescent CSCs could facilitate… read more here.
Keywords: quiescent cancer; recurrence; chemotherapy; cscs ... See more keywords
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells
Sign Up to like & getrecommendations! Published in 2021 at "Theranostics"
DOI: 10.7150/thno.63763
Abstract: Rationale: Recurrent and metastatic cancers often undergo a period of dormancy, which is closely associated with cellular quiescence, a state whereby cells exit the cell cycle and are reversibly arrested in G0 phase. Curative cancer… read more here.
Keywords: quiescent cells; quiescent cancer; cancer cells; cancer ... See more keywords